Volume 15 Number 2 June 2003

Keynote Papers

The role of statistics in pharmacogenomics
pages 3-13
Sandra Close Kirkwood
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Statistical analysis of forensic DNA: computational problems solved and to be solved
pages 15-26
Wing K. Fung
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Sample sizes of clinical trials: for science and decision making
pages 27-35
Byron Wm. Brown, Jr. and Jerry Halpern
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Clinical and Medical Evaluation Process

Enabling clinically based knowledge discovery in pharmacy claims data: an application in bioinformatics
pages 39-47
Jason Jones, Doug Stahl, Michael Nichol and Stanley P. Azen
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Statistical issues in the drug evaluation process: some issues in applying the ICH guidelines
pages 49-64
Tatsuya Isomura, Toshimitsu Hamasaki and Masashi Goto
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Stochastic process model for medical decision-making
pages 65-70
Takashi Namatame and Yumi Asahi
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Statistical Models for Biomedical Research

Analysing longitudinal claims cost data: a zero-augmented gamma mixed regression approach
pages 73-79
Andy H. Lee and Kelvin K. W. Yau
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Robust analysis of longitudinal data
pages 81-87
Bo Fu, Wing K. Fung and Xuming He
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Partial linear models with heteroscedastic variances
pages 89-104
Hua Liang and Wolfgang Härdle
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Nonparametric and semiparametric models in comparison of observations of a particle-size distribution
pages 105-122
Walter Liggett
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RIP-GAMs and classification trees in quantitative MRI
pages 123-134
Michael G. Schimek
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Power-transformation mixed effects model with applications to pharmacokinetics
pages 135-150
Takashi Daimon and Masashi Goto
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Sequential Methods for Biomedical Applications

Computational issues in information-based group sequential clinical trials
pages 153-167
KyungMann Kim, Anastasios A. Tsiatis and Cyrus R. Mehta
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A study of the sequential conditional test for contingency tables
pages 169-174
Toshio Sakata and Ryuichi Sawae
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Invariant confidence sequences for slippage of normal means
pages 175-179
Takahiko Hara
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Computational Issues in Statistical Data Analysis

Extensibilities of a Java-based statistical system
pages 183-192
Ikunori Kobayashi, Takeshi Fujiwara, Junji Nakano and Yoshikazu Yamamoto
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Evaluation of execution time on data analysis with parallel virtual machine
pages 193-199
Hiroyuki Minami, Yuriko Komiya and Masahiro Mizuta
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Symbolic Data Analysis

Neighborhood graphs in classification problems for symbolic data
pages 203-216
Manabu Ichino
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Clustering algorithms and Kohonen maps for symbolic data
pages 217-229
Hans-Hermann Bock
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Hierarchical and pyramidal clustering for symbolic data
pages 231-244
Paula Brito
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Categorical Data Analysis

Bootstrap calibration and empirical likelihood in the logistic regression model
pages 247-254
Michele La Rocca
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The performance of computer intensive methods for over-dispersed categorical data
pages 255-264
Yoshimichi Ochi
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Measures of variation explained by binary regression
pages 265-274
Norisuke Kawai and Masashi Goto
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Rank association measures for contingency tables
pages 275-280
Osamu Sugano
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Statistical evaluation of umbrella dose-response relationships
pages 281-293
Mitsumasa Baba, Masaki Fujisawa, Wataru Sakamoto and Masashi Goto
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VGAM family functions for categorical and genetic data
pages 295-304
Thomas W. Yee
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Functional Data Analysis

Geographically weighted functional multiple regression analysis: a numerical investigation
pages 307-317
Yoshihiro Yamanishi and Yutaka Tanaka
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Dissimilarity and related methods for functional data
pages 319-326
Shuichi Tokushige, Koichi Inada and Hiroshi Yadohisa
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Multidimensional scaling for dissimilarity functions with continuous argument
pages 327-333
Masahiro Mizuta
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Multidimensional Data Analysis

Computer intensive trials to determine the number of variables in PCA
pages 337-345
Masaya Iizuka, Yuichi Mori, Tomoyuki Tarumi and Yutaka Tanaka
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Sensitivity analysis in latent class analysis
pages 347-355
Tsukio Morita and Yutaka Tanaka
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Mixed data type and topological classification
pages 357-360
Karl-Ernst Biebler, Bernd Jäger and Michael Wodny and Elke Below
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A method to decide the dimension of data by the MDL criterion
pages 361-368
Tomoya Tokairin and Yoshiharu Sato
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